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In both natural and ar- (a) (b) Membrane protein Fluorescent reagent Bleached area Cell Label Bleach with laser Fluorescence recovery 123 Fluorescence before bleaching 3000 2000 1000 Bleach 50 immobile 50 mobile 50 100 150 Time (s) EXPERIMENTAL FIGURE 5-6 Fluorescence recovery after photobleaching (FRAP) experiments can quantify the lateral movement of proteins and lipids within the plasma membrane.

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