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Equations (5. Hormones or hormone-like agents can be administered to inhibit tumor growth by blocking or antagonizing CHAPTER 9 ONCOLOGY 209 214 Methods for High-Content, High-Throughput, Image-Based Cell Screening where g(I) is a smoothed version of the image, is the gradient operator, ||i j|| is the Euclidean distance between pixels i and j, and λ is a regularization term that balances between image-based and Euclidean distances, ranging from zero (distances from image features only) to infinity (Euclidean distance between pixels only).

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